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KMID : 0360220100510091203
Journal of the Korean Ophthalmological Society
2010 Volume.51 No. 9 p.1203 ~ p.1209
Predictable Factors of Postoperative Pain Following LASEK
Lee Jung-Hye

Ahn Kyeon
Chung Eui-Sang
Chung Tae-Young
Abstract
Purpose: To determine predictable factors of postoperative pain and cut-off values following LASEK eye surgery.

Methods: Thirty-three eyes of 17 patients who underwent LASEK from May to December 2008 were reviewed. For evaluation of predictive factors, patients¡¯ anxiety level was converted to APAIS, HADS, STAI, and VAS preoperatively. Substance P and prostaglandin E2 levels in tears, blood pressure, heart rate, and history of any previous surgery were determined before the procedure. Thirty minutes and 1 day after LASEK, the subjective degree of pain was scored.

Results: Patients with high Amsterdam preoperative anxiety scale (APAIS) and Visual analogue scale (VAS) scores showed more postoperative pain (p=0.04, p£¼0.001). Higher substance P and prostaglandin E2 levels were significantly related with more severe pain after LASEK (p£¼0.001, p£¼0.001). Postoperative pain increased significantly, according to cut-off values (p£¼0.05), APAIS and VAS scores greater than 6, substance P greater than 631.84 pg/ml, and prostaglandin E2 greater than 783.90 pg/ml.

Conclusions: The level of pain after LASEK surgery varies individually, and many factors, including physical and psychological variances, can affect the pain. With higher APAIS/VAS scores and higher concentrations of substance P, prostaglandin E2 portends more severe pain following LASEK.
KEYWORD
Anxiety, LASEK, Predictable factors, Postoperative pain
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